4G4 - Recognises the NS1 protein of most flaviviruses – suitable for use in IFA, ELISA, Western blot, antigen capture and immunohistochemistry.

This purchase is for an approximately 20 microgram/ml aliquot of supernatant that has not been further purified.  Costs for standard shipping are included in the price.

The product data sheet can be downloaded here. For technical enquiries, please email mozzymabs@uq.edu.au

The price exclude shipping.  Shipping will be organised and charged to your shipping agent account.  We can only ship with FedEx outside of Australia; we can only ship with LabCabs, TNT or Toll within Australia.  Please email your shipping agent account number to mozzymabs@uq.edu.au or we will not be able to process your order.

Target: Flavivirus NS1 protein

Produced in: Mouse

Isotype: IgG1

Specificity: Recognises most flaviviruses tested including Zika virus, West Nile virus, yellow fever virus, Japanese encephalitis virus, dengue type 2, dengue type 4, Murray Valley encephalitis virus and Kokobera virus. Does not recognise dengue type 1, dengue type 3, Edge Hill virus or Bamaga virus.

Applications: for Research Use Only.  IFA, ELISA, Western blot and immunohistochemistry

 IFA: shown to be effective following fixation using 4% formaldehyde or 100% acetone.

 ELISA: Can be used in fixed cell ELISA following 4% formaldehyde or ≥ 20% acetone.

Storage: Contains 0.02% sodium azide as a preservative. Store at 4 °C.

Can be aliquoted and stored frozen, but repeated freeze/thawing should be avoided.

A safety data sheet for 0.05% sodium azide solution can be accessed here.

Publications

Clark DC, Lobigs M, Lee E, Howard MJ, Clark K, Blitvich BJ, Hall RA. (2007) In situ reactions of monoclonal antibodies with a viable mutant of Murray Valley encephalitis virus reveal an absence of dimeric NS1 protein. J Gen Virol. 88(Pt 4):1175-83.

Prow NA, Setoh YX, Biron RM, Sester DP, Kim KS, Hobson-Peters J, Hall RA, Bielefeldt-Ohmann H. (2014) The West Nile virus-like flavivirus Koutango is highly virulent in mice due to delayed viral clearance and the induction of a poor neutralizing antibody response. J Virol. 88(17):9947-62.

Setoh YX, Prow NA, Peng N, Hugo LE, Devine G, Hazlewood JE, Suhrbier A, Khromykh AA. (2017) De Novo Generation and Characterization of New Zika Virus Isolate Using Sequence Data from a Microcephaly Case. mSphere. 2(3). pii: e00190-17.

THIS MATERIAL IS FOR RESEARCH USE ONLY AND CANNOT BE USED FOR CLINICAL OR DIAGNOSTIC PURPOSES

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